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Antidepressants for children and teens

Which antidepressants can children take?

The FDA has approved certain antidepressants for use in children and teenagers for different types of diagnoses. Antidepressants come with a medication guide that advises parents and caregivers about risks and precautions. Be sure to carefully read the medication guide and package insert, and discuss any questions with the prescribing physician and your pharmacist.

FDA-approved antidepressants for children and teenagers
Medication* Age (in years) Diagnosis
*Many of these drugs are also available in generic form. Recommended initial dose and maximum dose vary by age.
Clomipramine (Anafranil) 10 and older Obsessive-compulsive disorder (OCD)
Duloxetine (Cymbalta) 7 and older Generalized anxiety disorder
Escitalopram (Lexapro) 12 and older Major depressive disorder
Fluoxetine (Prozac) 8 and older Major depressive disorder
7 and older OCD
Fluvoxamine 8 and older OCD
Olanzapine and fluoxetine, combination drug (Symbyax) 10 and older Bipolar depression
Sertraline (Zoloft) 6 and older OCD

Antidepressants can also be used for other conditions. The antidepressant imipramine (Tofranil) is approved by the FDA to treat daytime or nighttime involuntary urination (childhood enuresis) in children 6 years of age and older.

Physicians may use their medical judgment to prescribe other antidepressants for children for what's called off-label use. This is a clinically common practice for many types of medications for both children and adults.